Population
Rabbit skeletal muscle (terminal cisternae of sarcoplasmic reticulum)
Design
Preclinical
Authors
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Hypothesis-generating for the 350 kDa protein in SR Ca2+ release; requires validation in intact cells and disease models.
The study demonstrates that the 350 kDa protein is a component of the Ca2+-release channel in the junctional face membrane of the sarcoplasmic reticulum.
Zorzato et al. (1989) studied this question.
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