June 15, 1975International Journal of Cancer
Influence of interferon on the synthesis of virus particles in oncornavirus carrier cell lines. III. Survey of effects on A‐, B‐ and C‐type oncornaviruses
Population
Murine cell lines carrying A-, B-, and C-type oncornaviruses sensitive to the antiviral effect of interferon
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Hypothesis-generating in murine models; leaves open whether interferon selectivity applies to human oncoviruses or warrants clinical exploration.
Structured PICO
P
Population
Murine cell lines carrying A-, B-, and C-type oncornaviruses sensitive to the antiviral effect of interferon
I
Intervention
Interferon pretreatment
O
Outcome
Synthesis and release of A-, B-, and C-type virusessurrogate
Interferon differentially affects the synthesis and release of A-, B-, and C-type oncornaviruses in murine cell lines.
Cite This Study
Billiau et al. (1975) studied this question.