Why the study?
The study investigated the 5-year stroke recurrence rate according to baseline mean carotid intima-media thickness with and without pravastatin treatment.
Does pravastatin 10 mg/day reduce stroke recurrence in patients with noncardioembolic infarction based on baseline carotid IMT?
Population
793 patients
Comparison
Pravastatin 10 mg/day vs control (nonstatin treatment)
Design
Prespecified post hoc analysis of a randomized trial
Follow-up
5 years
Authors
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Baseline carotid IMT stratifies recurrent stroke risk post-noncardioembolic stroke; leaves open whether IMT-guided therapy improves outcomes.
Does pravastatin 10 mg/day reduce stroke recurrence in patients with noncardioembolic infarction based on baseline carotid IMT?
Long-term pravastatin administration may prevent atherothrombotic brain infarction recurrence specifically in noncardioembolic stroke patients with high baseline carotid IMT.
Wada et al. (2019) studied this question.
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