Why the study?
Does acetazolamide reduce the severity of paralysis and alter serum insulin, glucose, and potassium levels in patients with familial periodic hypokalemic paralysis?
Population
4 patients with familial periodic hypokalemic paralysis
Comparison
Acetazolamide vs Untreated state
Design
Case_series
Authors
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May support acetazolamide prophylaxis in hypokalemic periodic paralysis; hypothesis-generating and requires randomized confirmation.
Does acetazolamide reduce the severity of paralysis and alter serum insulin, glucose, and potassium levels in patients with familial periodic hypokalemic paralysis?
Acetazolamide reduces the severity of paralytic attacks and lowers serum insulin and glucose levels in familial periodic hypokalemic paralysis, suggesting an indirect prophylactic action possibly via reduced absorption.
Torsten Johnsen (2009) studied this question.
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