Why the study?
Do atenolol, metoprolol, metoprolol durules, and slow-release oxprenolol reduce resting blood pressure compared to placebo in patients with moderate essential hypertension?
Population
25 patients with moderate essential hypertension (standing diastolic blood pressure 100-125 mmHg, phase 5)
Comparison
Four week periods of treatment with atenolol 100… vs Placebo for four week periods
Design
Single-blind
Follow-up
4 weeks per treatment period
Authors
Loading...
Atenolol or metoprolol durules may be preferred for 24-h BP control; extends beta-blocker comparisons but leaves open outcome data.
Do atenolol, metoprolol, metoprolol durules, and slow-release oxprenolol reduce resting blood pressure compared to placebo in patients with moderate essential hypertension?
Atenolol and metoprolol durules are more effective than standard metoprolol and slow-release oxprenolol at reducing resting blood pressure in patients with moderate essential hypertension.
J R Hampton (1981) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: