Why the study?
Does chronic ethanol ingestion induce left ventricular dysfunction and histological changes of cardiomyopathy in adult chickens?
Population
Adult chickens
Comparison
20% ethanol concentration given by gavage twice… vs Same volume of water by gavage twice a day…
Design
Preclinical
Follow-up
12 weeks
Authors
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New chicken model of alcohol cardiomyopathy now available; extends preclinical tools while leaving human translation open.
Does chronic ethanol ingestion induce left ventricular dysfunction and histological changes of cardiomyopathy in adult chickens?
This study establishes a novel chicken model of alcohol-induced cardiomyopathy that replicates the functional and histological changes seen in human disease.
Morris et al. (1999) studied this question.
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