Why the study?
Does epinephrine infusion alter systolic time intervals differently in patients with idiopathic hypertrophic subaortic stenosis compared to normal subjects?
Population
23 subjects (14 normal subjects and 9 patients with idiopathic hypertrophic subaortic stenosis)
Comparison
Epinephrine infusion vs Normal subjects vs. patients with idiopathic…
Design
Other
Authors
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Epinephrine response testing may refine diagnosis in obstructive cardiomyopathy; leaves open whether beta blockade improves long-term outcomes.
Does epinephrine infusion alter systolic time intervals differently in patients with idiopathic hypertrophic subaortic stenosis compared to normal subjects?
Epinephrine infusion unmasks a paradoxical lengthening of left ventricular ejection time in patients with idiopathic hypertrophic subaortic stenosis, a response that is reversible with beta blockade.
SALZMAN et al. (1971) studied this question.
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