Why the study?
Is the C825T polymorphism of the G protein β3-subunit gene associated with hypertension in black people of African origin?
Population
428 black men and women of African origin, aged 40 to 59 years, from a population-based survey.
Comparison
Presence of the T allele of the C825T… vs CC genotype (non-carriers of the T allele)
Design
Cross-sectional
Authors
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Should not yet change practice; hypothesis-generating for hypertension risk in African-origin populations pending replication.
Is the C825T polymorphism of the G protein β3-subunit gene associated with hypertension in black people of African origin?
The 825T allele of the G protein β3-subunit gene is highly prevalent in black populations of African origin and is significantly associated with an increased risk of hypertension.
Dong et al. (1999) studied this question.
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