Population
Anaesthetized rabbits
Comparison
Rilmenidine micro-injected into the rostral… vs Alpha-methylnoradrenaline, various antagonists…
Design
Preclinical
Authors
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RVLM mediates rilmenidine effects in rats; leaves open translation to human hypertension therapy.
The rostral ventrolateral medulla, rather than the nucleus tractus solitarius, is the primary site mediating the hypotensive and sympatho-inhibitory effects of rilmenidine.
Head et al. (1998) studied this question.
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