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July 1, 1998British Journal of Haematology

Associations of protein C and protein S with serum lipid concentrations

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Why the study?

Are protein C and protein S levels associated with serum lipid concentrations in adults?

Population

150 adults, age range 23-80 years, identified from a single general practice by stratified random sampling…

Design

Cross-sectional

Authors

MMaccallumSt Bartholomew's HospitalHHowarthSt Bartholomew's Hospital

Discussion

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Implication

Lipid variation may confound protein C testing; leaves open whether adjustment refines deficiency diagnosis.

Structured PICO

Are protein C and protein S levels associated with serum lipid concentrations in adults?

P
Population
150 adults (73 male, 77 female), age range 23-80 years, identified from a single general practice by stratified random sampling within sex and decade of age.
O
Outcome
Association between protein C and protein S levels (activity and antigen) and serum lipid concentrations (total cholesterol, high-density cholesterol, and triglyceride).surrogate

Physiological variations in serum lipids are significantly associated with protein C and protein S levels, suggesting lipid profiles should be considered when diagnosing deficiencies.

Cite This Study

Maccallum et al. (1998) studied this question.

synapsesocial.com/papers/6a8729242527c72a71a25df2https://doi.org/10.1046/j.1365-2141.1998.00800.x
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Also Consider

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