Why the study?
Does moderate concentric left ventricular hypertrophy in renal hypertensive dogs alter left ventricular pump performance compared to normal dogs?
Population
Dogs with chronic renovascular hypertension and moderate concentric left ventricular hypertrophy, and normal…
Comparison
Assessment of open-chest left ventricular pump… vs Normal dogs
Design
Preclinical
Authors
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Enhanced LV performance in this canine LVH model should not alter practice; leaves open translation to human disease or outcomes.
Does moderate concentric left ventricular hypertrophy in renal hypertensive dogs alter left ventricular pump performance compared to normal dogs?
Moderate concentric left ventricular hypertrophy in renal hypertensive dogs is associated with increased left ventricular pump performance, likely due to additional muscle and an increased wall-to-lumen ratio.
Broughton et al. (1986) studied this question.
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