Why the study?
Do structural and functional brain indices predict the success of pharmacological treatment of hypertension in previously unmedicated individuals?
Population
45 previously unmedicated individuals with essential hypertension
Design
RCT, randomly assigned, double-blind
Follow-up
1 year
Authors
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Brain indices may help predict antihypertensive response in unmedicated patients; extends neuroimaging biomarkers for hypertension treatment.
Do structural and functional brain indices predict the success of pharmacological treatment of hypertension in previously unmedicated individuals?
Pretreatment structural and functional brain indices, reflecting brain aging, can predict the blood pressure response to pharmacological treatment in hypertensive patients.
Jennings et al. (2008) studied this question.
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