Population
Rat left ventricular (LV) slices (300 microns in thickness)
Comparison
Electrical field stimulation in an air-tight… vs No electrical field stimulation and Ca-free…
Design
Preclinical
Authors
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Should not alter clinical management of myocardial energetics; leaves open the role of excitation-contraction coupling in intact human hearts.
A novel method for measuring mechanically unloaded myocardial VO2 in rat LV slices suggests that stimulation-induced VO2 increases are primarily driven by excitation-contraction coupling.
Yasuhara et al. (1996) studied this question.
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