July 1, 1982Journal of Applied Physiology

Cardiac output as a controller of ventilation through changes in right ventricular load

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Population

Spontaneous breathing anesthetized dogs

Design

Preclinical

Authors

PJPeter M. JonesKing's College London AHA. HuszczukSt George's Hospital KWK. WassermanUCLA Medical Center

Discussion

Member takes

Implication

RV strain may control ventilation in animals; leaves open human translation and causality.

Structured PICO

Population

Spontaneous breathing anesthetized dogs

Intervention

Alteration of right ventricular load via changes in cardiac output (isoproterenol 0.7-1.2 micrograms/min or vasopressin 0.3-0.5 U/min) or partial balloon obstruction of the RV outflow

Outcome

Ventilatory responses (expired minute ventilation, VE) to changes in right ventricular strain (moving average RV pressure)surrogate

Right ventricular strain may act as a controller of ventilation and provide a physiological link between cardiac output and minute ventilation.

Cite This Study

Jones et al. (1982) studied this question.

synapsesocial.com/papers/6a882b1f8e586ad1c8a54473 https://doi.org/10.1152/jappl.1982.53.1.218

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Cardiac output as a controller of ventilation through changes in right ventricular load

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Cardiac output as a controller of ventilation through changes in right ventricular load

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider