Why the study?
Does antirenin therapy improve blood pressure in patients with essential hypertension and Goldblatt-type hypertension?
Does antirenin therapy improve blood pressure in patients with essential hypertension and Goldblatt-type hypertension?
The concept of discordant nephron function explains why ACE inhibition often corrects 'normal' renin hypertension, highlighting the role of antirenin therapy.
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May support antirenin therapy in normal-renin hypertension; hypothesis-generating and requires prospective trials before practice change.
John H. Laragh (1991) studied this question.
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