Key result
Chronic lithium therapy overdose caused bizarre ECG changes mimicking inferior myocardial infarction and QTc prolongation, which partially recovered after hemodialysis.
Case Report (n=1)
Chronic lithium therapy and overdose can cause bizarre ECG changes mimicking inferior myocardial infarction and QTc prolongation, which may partially resolve with hemodialysis.
Clinicians should consider lithium toxicity in MI-mimicking ECGs with QTc prolongation; leaves open questions on hemodialysis efficacy in larger cohorts.
Cardiotoxicity that results from lithium overdose is uncommon and electrocardiographic (ECG) changes are rarely reported. However, some authors have specifically reported the occurrence of ischemic ECG changes due to a lithium overdose. This article describes a case that is demonstrating ECG changes that mimic inferior myocardial infarction during the course of chronic lithium treatment and showing QTc prolongation in this patient. The patients' ECG changes were partially recovered after hemodialysis.
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Kayrak et al. (2010) conducted a case report in Lithium cardiotoxicity (n=1). Chronic lithium therapy was evaluated on Electrocardiographic changes. Chronic lithium therapy overdose caused bizarre ECG changes mimicking inferior myocardial infarction and QTc prolongation, which partially recovered after hemodialysis.
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