Why the study?
Does the duration of OKT3 treatment influence the development of a repetitive histologic pattern of vascular cardiac allograft rejection in heart transplant recipients?
Population
344 heart transplant recipients
Design
Cohort
Authors
Loading...
Associated with vascular rejection and reduced survival; hypothesis-generating and should not yet change OKT3 use in heart transplant recipients.
Does the duration of OKT3 treatment influence the development of a repetitive histologic pattern of vascular cardiac allograft rejection in heart transplant recipients?
Longer duration of OKT3 treatment for early rejection prophylaxis is associated with an increased risk of developing a repetitive histologic pattern of vascular cardiac allograft rejection, which in turn decreases allograft survival.
Hong et al. (1996) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: