Population
Dog coronary arteries (proximal and distal)
Comparison
Endothelium-derived relaxing factor and nitric… vs Proximal versus distal coronary arteries
Design
Preclinical
Authors
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Differential basal EDRF effects versus NO in porcine coronaries; leaves open translation to human physiology or therapy.
Basally released EDRF elicits different relaxation responses in proximal versus distal coronary arteries, suggesting it differs from NO.
Hoeffner et al. (1989) studied this question.
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