Why the study?
Does diltiazem preserve coronary vascular functional integrity in isolated rabbit hearts during reperfusion after ischemia?
Population
Isolated rabbit hearts subjected to 30 min of global, no-flow ischemia
Comparison
Diltiazem 4 microM vs Ischemic hearts without diltiazem and…
Design
Preclinical
Follow-up
5 hours of continuous perfusion / reperfusion after 30 min…
Authors
Loading...
May support diltiazem vascular protection in rabbit ischemia-reperfusion; leaves open clinical translation.
Does diltiazem preserve coronary vascular functional integrity in isolated rabbit hearts during reperfusion after ischemia?
Diltiazem protects ischemic myocardium in isolated rabbit hearts by preserving vascular functional integrity during reperfusion.
Tilton et al. (1985) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: