February 1, 1984Acta Physiologica Scandinavica

Interaction between “mental stress” and baroreceptor reflexes concerning effects on heart rate, mean arterial pressure and renal sympathetic activity in conscious spontaneously hypertensive rats

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Population

Conscious spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY)

Comparison

Acute 'mental stress' superimposed on baroreflex… vs Normotensive Wistar Kyoto rats subjected to the…

Design

Preclinical

Authors

SLS. LundinKarolinska Institutet SRSven‐Erik RickstenUniversity of Gothenburg PTPeter ThorénCross-Cutting Cardiology

Discussion

Member takes

Implication

Stress overrides baroreflex inhibition in hypertensive rats; leaves open relevance to human hypertension.

Structured PICO

Population

Conscious spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY)

Intervention

Acute 'mental stress' (sudden blowing of air) superimposed on baroreflex activation (phenylephrine infusion)

Comparator

Normotensive Wistar Kyoto rats (WKY) subjected to the same conditions

Outcome

Changes in heart rate (HR), mean arterial pressure (MAP), and renal sympathetic nerve activity (RSNA)surrogate

In spontaneously hypertensive rats, environmental alerting stimuli induce powerful defense reactions that overcome baroreflex inhibitory influences on sympathetic activity, unlike in normotensive rats.

Cite This Study

Lundin et al. (1984) studied this question.

synapsesocial.com/papers/6a8930bae88fc9ac761a34db https://doi.org/10.1111/j.1748-1716.1984.tb00134.x

Topics

Hypertension management

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Interaction between “mental stress” and baroreceptor reflexes concerning effects on heart rate, mean arterial pressure and renal sympathetic activity in conscious spontaneously hypertensive rats

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Interaction between “mental stress” and baroreceptor reflexes concerning effects on heart rate, mean arterial pressure and renal sympathetic activity in conscious spontaneously hypertensive rats

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider