Population
Hypophysectomized-nephrectomized dogs and simple hypophysectomized dogs
Comparison
Injections of hog renin extracts, semipurified… vs Erythropoietin preparations
Design
Preclinical
Authors
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No immediate clinical implications; leaves open translational relevance of renin-angiotensin effects on aldosterone to humans.
This preclinical study provides early evidence that the renin-angiotensin system plays a role in regulating aldosterone secretion.
Mulrow et al. (1963) studied this question.
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