Why the study?
No single approach to endocardial LAPW isolation exists and relative success compared to PVI alone has been mixed, leading to the development of the hybrid convergent procedure.
Does the hybrid convergent procedure improve freedom from atrial arrhythmias compared to endocardial catheter ablation in patients with drug-refractory persistent and long-standing persistent AF?
Does the hybrid convergent procedure improve freedom from atrial arrhythmias compared to endocardial catheter ablation in patients with drug-refractory persistent and long-standing persistent AF?
The hybrid convergent procedure, combining epicardial and endocardial ablation, may improve outcomes and reduce AF burden in difficult-to-treat patients with advanced AF compared to endocardial ablation alone.
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Supports hybrid convergent evaluation in refractory persistent AF; leaves open practice change pending randomized trials.
David B. DeLurgio (2022) studied this question.
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