Why the study?
Does living, attenuated, oral poliovirus vaccine (OPV) cause paralytic poliomyelitis in adult vaccinees?
Population
Adults receiving living, attenuated, oral poliovirus vaccine (OPV)
Design
Case_series
Authors
Loading...
May signal rare OPV-associated paralysis in adults; leaves open causality and warrants controlled studies before practice change.
Does living, attenuated, oral poliovirus vaccine (OPV) cause paralytic poliomyelitis in adult vaccinees?
A small cluster of paralytic poliomyelitis cases following OPV administration in 1962 raised safety concerns regarding its use in adult vaccinees.
Henry M. Gelfand (1963) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: