Key result
The hypertriglyceridemic waist phenotype was associated with a 2.3-fold increased risk of incident hypertension over 7 years compared to normal triglyceride levels and waist circumference.
Effect estimate: 2.3-fold increased risk
A letter to the editor discussing the utility of VAI and HTGW phenotype for predicting incident hypertension and diabetes in an Iranian cohort.
VAI and HTGW Phenotype and Hypertension Risk ulation.Previous studies have reported a high risk of diabetes development in subjects with the HTGW phenotype and a high risk of coronary artery calcification in subjects with a high baseline VAI [9].Therefore, I wonder if similar results would be observed in this study population.Second, I wonder if the authors thought of analyzing whether metabolically healthy obese (MHO) subjects were present in this study population [12].The debate about the existence of MHO individuals in various ethnic populations continues [13].It would be interesting if the authors analyzed the level of risk that MHO subjects had for developing diabetes or HTN, since this study population is at a high risk for diabetes.Lastly, I think the authors should interpret the results with caution, since this study population is already at a high risk for metabolic derangement and diabetes.I want to congratulate the authors on this beautiful work and expect to see in the future many excellent studies emerging from this well-structured Iranian cohort.
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Eun‐Jung Rhee (2017) conducted a letter in Risk of incident hypertension (n=1,375). Hypertriglyceridemic waist (HTGW) phenotype vs. Normal triglyceride level and normal waist circumference was evaluated on Incident hypertension (2.3-fold increased risk). The hypertriglyceridemic waist phenotype was associated with a 2.3-fold increased risk of incident hypertension over 7 years compared to normal triglyceride levels and waist circumference.
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