Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
October 15, 2022Cardiovascular DiabetologyOpen Access

Participants in the highest quartile of the TyG index had a 5.35-fold increased risk of T2DM (OR 5.35, 95% CI 4.33-6.64) compared to those in the lowest quartile.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Data are limited on whether novel, easily measured lipid indices independently predict type 2 diabetes mellitus in hypertensive patients.

Do novel lipid indicators (HTGW, TyG, LAP, VAI) predict the risk of type 2 diabetes mellitus in hypertensive patients?

Population

5321 hypertensive patients from the Guangzhou Heart Study baseline survey

Comparison

Levels of HTGW phenotype, TyG index, LAP, and VAI

Design

Cross-sectional study

Authors

HDHai DengElectrophysiologyPHPeng HuTongji UniversityHLHuoxing Li

Discussion

Loading...

Member takes

Overview

May aid T2DM risk stratification in hypertensives; leaves open prospective validation and incremental predictive value.

Structured PICO

Do novel lipid indicators (HTGW, TyG, LAP, VAI) predict the risk of type 2 diabetes mellitus in hypertensive patients?

P
Population
5321 hypertensive patients from the baseline survey of the Guangzhou Heart Study
I
Intervention
Hypertriglyceridemic-waist phenotype (HTGW), triglyceride glucose (TyG) index, lipid accumulation product (LAP), and visceral adiposity index (VAI)
C
Comparator
Lowest quartile of the respective indices or absence of HTGW
O
Outcome
Risk of type 2 diabetes mellitus (T2DM)

Novel lipid indicators, particularly the TyG index, are strongly associated with an increased risk of type 2 diabetes in Chinese hypertensive patients and may serve as simple risk assessment tools.

Cite This Study

Deng et al. (2022) studied this question.

synapsesocial.com/papers/6a7c276dc2a640f0bcdf989fhttps://doi.org/10.1186/s12933-022-01660-z
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk of type 2 diabetes mellitus associated with lipid-related metabolic indicators: a diabetes family cohort study in China2026
  2. 2Anthropometric and lipid indices in relation to prediabetes and diabetes: A cross-sectional study in resource-limited areas of northwestern China.2025
  3. 3The association of triglyceride-glucose and triglyceride-glucose related indices with the risk of heart disease in a national cohort study2025 · 21 citations
  4. 4Association between novel obesity- and lipid-related indices and diabetes across different FBG among elderly: a prospective cohort study2026
  5. 5THE TRIGLYCERIDE GLUCOSE CHINESE VISCERAL ADIPOSITY INDEX, A NOVEL MARKER INTEGRATING LIPID METABOLISM AND VISCERAL ADIPOSITY, IS ASSOCIATED WITH NEW-ONSET HYPERTENSION IN MIDDLE-A2026