Key result
Genetic factors significantly contributed to arterial structure and function, with adjusted heritability estimates of 0.26 for pulse wave velocity, 0.35 for IMT, and 0.21 for plaque score (P<0.001).
Population
930 individuals connected in a single pedigree from an isolated population (participants of the Erasmus…
Design
Cross-sectional
Authors
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Supports genetic studies of arterial phenotypes; leaves open clinical utility for stroke risk prediction.
Observational (n=930)
Effect estimate: Adjusted heritability 0.26 for PWV, 0.35 for IMT, 0.21 for plaque score
p-value: p=<0.001
Genetic factors significantly contribute to arterial structure and function, explaining approximately 12% of the total variability for PWV, IMT, and plaque score.
Sayed‐Tabatabaei et al. (2005) reported an observational. Genetic factors (heritability) was evaluated on Heritability of carotid-femoral pulse wave velocity (PWV), carotid intima media thickness (IMT), and carotid plaque score (Adjusted heritability 0.26 for PWV, 0.35 for IMT, 0.21 for plaque score, p=<0.001). Genetic factors significantly contributed to arterial structure and function, with adjusted heritability estimates of 0.26 for pulse wave velocity, 0.35 for IMT, and 0.21 for plaque score (P<0.001).
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