Why the study?
Does almokalant have negative inotropic effects in dogs with acute ischaemic heart failure?
Does almokalant have negative inotropic effects in dogs with acute ischaemic heart failure?
Almokalant, a class III antiarrhythmic, prolongs ventricular repolarization without exerting negative inotropic effects in a canine model of acute ischaemic heart failure.
No takes yet. Share an insight, caveat, or question.
No negative inotropy in this canine ischaemic HF model; leaves open translation to human use.
Mortensen et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: