Key result
Carriage of the T-786C polymorphism in the eNOS gene was associated with an increased risk of coronary artery disease in a Chinese Han population (OR 1.739; 95% CI 1.215-2.490).
Why the study?
Is the T-786C polymorphism in the eNOS gene associated with an increased risk of coronary artery disease in a Chinese Han population?
Case-Control (n=622)
Is the T-786C polymorphism in the eNOS gene associated with an increased risk of coronary artery disease in a Chinese Han population?
Odds Ratio: 1.739 (95% CI 1.215–2.49)
The T-786C polymorphism of the eNOS gene appears to be an independent genetic risk factor for coronary artery disease in the Chinese Han population.
No takes yet. Share an insight, caveat, or question.
May flag elevated CAD risk with T-786C in Chinese Han; hypothesis-generating and requires prospective validation before any clinical use.
Han et al. (2010) conducted a case-control in Coronary artery disease (CAD) (n=622). T-786C polymorphism in the eNOS gene vs. Individuals without the minor allele was evaluated on Risk of coronary artery disease (OR 1.739, 95% CI 1.215-2.490). Carriage of the T-786C polymorphism in the eNOS gene was associated with an increased risk of coronary artery disease in a Chinese Han population (OR 1.739; 95% CI 1.215-2.490).
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