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March 1, 1933The Journal of Experimental MedicineOpen Access

Nutritional Encephalomalacia in Chicks

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Authors

APA. M. PappenheimerCalifornia Institute of TechnologyMGMarianne GoettschColumbia University

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Overview

Experimental study reveals age-dependent susceptibility to nutritional encephalomalacia across multiple chick breeds, indicating early natural feeding confers protection regardless of growth rate.

Key Points

  • To evaluate how age, duration of preliminary natural feeding, growth rate, and breed influence chick susceptibility to nutritional encephalomalacia.
  • Fed chicks an experimental diet to induce nutritional encephalomalacia up to approximately two months of age following varied preliminary periods on a natural foods diet.
  • Tracked disease incidence, latency to symptom appearance, and growth rates across four distinct breeds: White Leghorns, Barred Plymouth Rocks, Rhode Island Reds, and White Wyandottes.
  • Chicks developed nutritional encephalomalacia up to two months of age, with disease incidence progressively decreasing and symptom onset accelerating as the preliminary natural feeding duration increased.
  • Disease occurrence did not correlate with chick growth rate, and all four tested breeds demonstrated equal susceptibility to the condition.

Cite This Study

Pappenheimer et al. (1933) studied this question.

synapsesocial.com/papers/6a8a3fc7755d28965dfd61b0https://doi.org/10.1084/jem.57.3.365
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