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February 1, 1969The Journal of Clinical Endocrinology & Metabolism

Studies with the Radioimmunoassay for Angiotensin II, and Its Application to Measurement of Renin Activity

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Population

Normal subjects and anephric subjects

Design

Other

Authors

LPLot B. PageGeneral / Preventive / LipidsEHEdgar HaberGeneral / Preventive / LipidsAKANDREW Y. KIMURATufts University

Discussion

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Implication

Normative angiotensin II and renin values established in healthy subjects; leaves open validation for hypertension or heart failure monitoring.

Structured PICO

P
Population
Normal subjects and anephric subjects
I
Intervention
Radioimmunoassay for angiotensin II
O
Outcome
Plasma angiotensin II concentration and renin activitysurrogate

The study describes an improved radioimmunoassay for angiotensin II that can also measure renin activity, demonstrating expected physiological changes with sodium intake and diuretics.

Cite This Study

Page et al. (1969) studied this question.

synapsesocial.com/papers/6a8a41fe273d243e4992f762https://doi.org/10.1210/jcem-29-2-200
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Radioimmunoassay of Angiotensin I: Comparison of Two Renin Activity Methods and Use for Other Measurements of the Renin System1972 · 55 citations
  2. 2Application of a Radioimmunoassay for Angiotensin I to the Physiologic Measurements of Plasma Renin Activity in Normal Human Subjects<sup>1</sup>1969 · 2,239 citations
  3. 3Radioimmunoassay of Angiotensin II in Peripheral Venous Plasma: Effects of Diet and Posture and Application to Measurement of Renal Venous Renin Ratio*1971 · 5 citations
  4. 4Application of a Radioimmunoassay for Angiotensin I to the Measurement of Plasma Renin in Rabbits, and Comparison with a Biological Assay of Plasma Renin Activity1975 · 6 citations
  5. 5Measurement of Plasma Renin Activity as a Valid Estimation of Plasma Angiotensin Status1978 · 3 citations