Why the study?
Does short term continuous positive airway pressure (CPAP) increase muscle sympathetic nerve activity in patients with congestive heart failure?
Population
10 patients with congestive heart failure and 10 healthy subjects matched for age, sex, and weight.
Comparison
Short term continuous positive airway pressure… vs Normal breathing and mask breathing
Follow-up
short term (during intervention)
Authors
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Alerts to possible acute sympathetic and BP rises with CPAP in HF; hypothesis-generating and should not change practice yet.
Does short term continuous positive airway pressure (CPAP) increase muscle sympathetic nerve activity in patients with congestive heart failure?
Short term CPAP elicits sympathetic activation and increases blood pressure in patients with chronic heart failure, likely due to baroreceptor unloading.
S Heindl (2001) studied this question.
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