Why the study?
Does felodipine reduce blood pressure and peripheral resistance without decreasing cardiac output in hypertension?
Population
Animals and humans with essential hypertension, including a specific cohort of 16 males with initial…
Design
Review
Authors
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May support felodipine's vasodilatory profile preserving cardiac output in hypertension; leaves open confirmation in larger trials.
Does felodipine reduce blood pressure and peripheral resistance without decreasing cardiac output in hypertension?
Felodipine effectively lowers blood pressure by reducing total peripheral resistance without compromising cardiac output or causing chronic reflex tachycardia.
Per Lund‐Johansen (1990) studied this question.
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