Why the study?
Does the DCP1 gene I/D polymorphism influence plasma DCP1 activity similarly in severely hypertensive and normotensive Caucasian subjects?
Population
129 Caucasian subjects, comprising 35 patients with severe, familial essential hypertension and 94…
Comparison
Genotyping for the 287 bp insertion/deletion… vs Comparison across genotypes and between…
Design
Cross-sectional
Authors
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Supports equivalent DCP1 genotype-activity relationship in hypertensives and normotensives; hypothesis-generating, should not yet change practice.
Does the DCP1 gene I/D polymorphism influence plasma DCP1 activity similarly in severely hypertensive and normotensive Caucasian subjects?
The I/D polymorphism of the DCP1 gene influences plasma ACE activity similarly in both severely hypertensive and normotensive Caucasian subjects.
Morris et al. (1994) studied this question.
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