June 1, 1997Journal of Women s Health
Prognostic Value of Cholesterol in Women of Different Ages
Why the study?
Does total cholesterol level predict mortality in women of different ages?
Population
2,873 women in the Framingham Heart Study
Comparison
Total cholesterol levels vs Different cholesterol levels across age groups
Design
Cohort
Follow-up
median 31 years
Authors
Discussion
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Member takes
Implication
Questions benefit of low cholesterol targets in women >55; hypothesis-generating, should not change practice.
Structured PICO
Does total cholesterol level predict mortality in women of different ages?
P
Population
2,873 women in the Framingham Heart Study
I
Intervention
Total cholesterol levels
C
Comparator
Different cholesterol levels across age groups
O
Outcome
All-cause mortalityhard clinical
The study challenges the hypothesis that cholesterol < 200 mg/dl leads to decreased mortality in women over 55, demonstrating U-shaped or inverse relationships in older age groups.
Cite This Study
Emond et al. (1997) studied this question.