January 1, 1996Transplantation
Coronary Artery Intimal Thickening in the Transplanted Heart
Population
116 adult heart transplant recipients, mean age 44.7 +/- 12.0 years, 89 men and 27 women, undergoing annual…
Design
Cross-sectional
Follow-up
3.4 +/- 2.7 years after transplantation
Authors
Discussion
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Member takes
Implication
Higher triglycerides and weight associate with transplant vasculopathy severity; hypothesis-generating for prospective intervention trials.
Structured PICO
P
Population
116 adult heart transplant recipients, mean age 44.7 +/- 12.0 years, 89 men and 27 women, undergoing annual coronary angiography and intracoronary ultrasound 3.4 +/- 2.7 (range, 1.0-14.6) years after transplantation.
O
Outcome
Coronary artery intimal thickening and luminal stenosis (transplant coronary artery disease)surrogate
Higher fasting plasma triglyceride levels and body weight, rather than acute rejection, are independent correlates of transplant coronary artery disease severity.
Cite This Study
Rickenbacher et al. (1996) studied this question.