Population
Anesthetized rats (kidney homogenates)
Comparison
Mercuric chloride, sodium potassium tartrate… vs Control values (normal rat kidney homogenates)
Design
Preclinical
Authors
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Highlights tubular angiotensinase localization in animal cortex; leaves open human relevance and therapeutic implications.
This preclinical study demonstrates that angiotensinase activity is primarily localized in the renal cortex and is significantly reduced by the destruction of proximal and distal renal tubular cells.
Itskovitz et al. (1966) studied this question.
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