Key result
Angiotensin converting enzyme I/D genotype was not significantly related to blood pressure (P=0.16), although the DD genotype increased ACE activity by 35% compared with the II genotype.
Population
500 community residents in Kingston, Jamaica (black population)
Design
Cross-sectional
Authors
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Does not support ACE I/D genotyping for BP risk; leaves open its role in other cardiovascular phenotypes.
Cross-Sectional (n=500)
No
p-value: p=0.16
In a Jamaican population, the ACE I/D polymorphism influences serum ACE activity but is not independently associated with blood pressure.
Terrence Forrester (1997) conducted a cross-sectional in Blood pressure (n=500). Angiotensin converting enzyme I/D polymorphism was evaluated on blood pressure (p=0.16). Angiotensin converting enzyme I/D genotype was not significantly related to blood pressure (P=0.16), although the DD genotype increased ACE activity by 35% compared with the II genotype.
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