Why the study?
Does a single oral dose of minoxidil effectively lower acute blood pressure elevations in chronically hypertensive children with renal disease?
Population
13 chronically hypertensive children 2 to 18 years of age experiencing 23 episodes of acute elevation of…
Comparison
Single oral dose of minoxidil, administered… vs Single oral dose of minoxidil < 0.2 mg/kg.
Design
Case_series
Follow-up
4 hours
Authors
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May support 0.2 mg/kg minoxidil for acute pediatric hypertension; hypothesis-generating and requires prospective validation.
Does a single oral dose of minoxidil effectively lower acute blood pressure elevations in chronically hypertensive children with renal disease?
A single oral dose of minoxidil at 0.2 mg/kg effectively and safely reduces acute blood pressure elevations to safe levels within four hours in chronically hypertensive children with renal disease.
Strife et al. (1986) studied this question.
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