Population
Isolated rat hearts (n=36)
Comparison
Ischaemic preconditioning plus L-arginine before… vs Global ischaemia alone, ischaemic…
Design
Preclinical
Follow-up
120 min of reperfusion
Authors
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May augment experimental cardioprotection; leaves open translation to human ischaemic preconditioning.
L-arginine enhances the cardioprotective effects of ischaemic preconditioning in isolated rat hearts, improving functional recovery and reducing infarct size.
Suematsu et al. (2001) studied this question.
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