Why the study?
Does heparin treatment prolong platelet survival in human subjects?
Population
Human subjects (specific demographics and sample size not stated)
Comparison
Heparin at two levels of dosage, including 8000… vs Control periods without heparin
Design
Other
Authors
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High-dose heparin may prolong platelet survival; hypothesis-generating observation requiring randomized trials before any practice change.
Does heparin treatment prolong platelet survival in human subjects?
Intensive heparin therapy (8000 units 8-hourly) prolongs platelet survival and reduces turnover, though individual responses vary and platelet adhesiveness may paradoxically increase as the effect wears off.
Mustard et al. (1963) studied this question.
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