January 17, 2013Pakistan Journal of Medical SciencesOpen Access

Evaluation of Aspirin and Clopidogrel resistance in patients with Acute Coronary Syndrome by using Adenosine Diposphate Test and Aspirin Test

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Population

64 patients, including 57 with acute coronary syndrome and 7 scheduled for elective percutaneous coronary…

Design

Cross-sectional

Authors

OIOsama IbrahimBoston Children's Hospital MOM OtehUniversity Kebangsaan Malaysia Medical Centre AAA Syukur AUniversity Kebangsaan Malaysia Medical Centre

Discussion

Member takes

Implication

Antiplatelet non-response in PCI patients is hypothesis-generating; does not support routine testing or practice changes.

Structured PICO

Population

64 patients, including 57 with acute coronary syndrome (ACS) and 7 scheduled for elective percutaneous coronary intervention (PCI).

Intervention

Platelet function testing using the Multiplate Platelet Function Analyzer (Adenosine Diphosphate Test and Aspirin Test) after loading with 300 mg clopidogrel and 300 mg aspirin, or while on a stable daily dose of 75 mg clopidogrel.

Outcome

Aspirin and clopidogrel resistance/non-responsesurrogate

A notable proportion of patients undergoing PCI exhibit resistance to clopidogrel (21.9%) and aspirin (4.69%) when assessed by the Multiplate Platelet Function Analyzer.

Cite This Study

Ibrahim et al. (2013) studied this question.

synapsesocial.com/papers/6a8b923ede5ec4e001e3c741 https://doi.org/10.12669/pjms.291.2820

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Evaluation of Aspirin and Clopidogrel resistance in patients with Acute Coronary Syndrome by using Adenosine Diposphate Test and Aspirin Test

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Evaluation of Aspirin and Clopidogrel resistance in patients with Acute Coronary Syndrome by using Adenosine Diposphate Test and Aspirin Test

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider