January 1, 1977Current Medical Research and Opinion

Control of hypertension with single daily doses of sotalol hydrochloride

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Why the study?

Does once-daily sotalol control blood pressure in previously untreated hypertensive patients?

Population

12 previously untreated hypertensive patients

Design

Case_series

Follow-up

3 months (plus 3 weeks titration)

Authors

RGRoger GabrielCleveland Clinic

Discussion

Member takes

Implication

May support once-daily sotalol for BP control in untreated hypertension; hypothesis-generating case report requiring randomized confirmation.

Structured PICO

Does once-daily sotalol control blood pressure in previously untreated hypertensive patients?

Population

12 previously untreated hypertensive patients

Intervention

Sotalol once-daily (mean dose 190 mg, up to 320 mg or less in 8/12 patients) for 3 months after an initial mean 3-week titration period

Outcome

Blood pressure control (diastolic pressure stabilized at less than 100 mmHg)surrogate

Once-daily sotalol effectively maintains blood pressure control in previously untreated hypertensive patients.

Cite This Study

Roger Gabriel (1977) studied this question.

synapsesocial.com/papers/6a8ba8bd2448cb7c68338ffe https://doi.org/10.1185/03007997609112010

Topics

Hypertension management

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Implication

May support once-daily sotalol for BP control in untreated hypertension; hypothesis-generating case report requiring randomized confirmation.

Control of hypertension with single daily doses of sotalol hydrochloride

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Control of hypertension with single daily doses of sotalol hydrochloride

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider