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January 1, 1994Journal of Clinical MicrobiologyOpen Access

Comparison of rapid detection methods for influenza A virus and their value in health-care management of institutionalized geriatric patients

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Why the study?

Do rapid detection methods accurately identify influenza A virus compared to culture isolation in geriatric patients?

Population

160 geriatric patients with suspected influenza illness

Comparison

Rapid detection methods for influenza A virus vs Culture isolation

Design

Cross-sectional

Authors

GLG LeonardiUniversity of MilanHLHelaine B. LeibNew York State Department of HealthGBGuthrie S. BirkheadUniversity at Albany, State University of New York

Discussion

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Implication

Rapid tests may aid influenza A detection in geriatric patients; leaves open prospective validation before changing infection control practice.

Structured PICO

Do rapid detection methods accurately identify influenza A virus compared to culture isolation in geriatric patients?

P
Population
160 geriatric patients with suspected influenza illness
I
Intervention
Rapid detection methods for influenza A virus (Directigen FLU-A, Prima EIA, and direct immunofluorescence testing [IFA])
C
Comparator
Culture isolation
O
Outcome
Sensitivity and specificity for identifying influenza A virussurrogate

Rapid detection methods like EIA and IFA show high sensitivity and specificity for influenza A compared to culture, enabling timely antiviral therapy and infection control in geriatric institutions.

Cite This Study

Leonardi et al. (1994) studied this question.

synapsesocial.com/papers/6a8be7fd3fd21775a533c4fehttps://doi.org/10.1128/jcm.32.1.70-74.1994
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Also Consider

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  1. 1Impact of influenza epidemics on mortality in the United States from October 1972 to May 1985.1987 · 322 citations
  2. 2The Roles of Vaccination and Amantadine Prophylaxis in Controlling an Outbreak of Influenza A (H3N2) in a Nursing Home1988 · 110 citations
  3. 3Rapid detection of respiratory viruses by shell vial culture and direct staining by using pooled and individual monoclonal antibodies1992 · 100 citations