Why the study?
Does cilazapril 2.5 mg or 5 mg once daily reduce ambulatory blood pressure compared to placebo in patients with mild to moderate essential hypertension?
Population
42 patients with mild to moderate essential hypertension
Comparison
Cilazapril 2.5 mg or 5 mg once daily for 4 weeks vs Placebo for 4 weeks
Design
RCT, randomized, double-blind
Follow-up
4 weeks
Authors
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Supports cilazapril 2.5 mg for equivalent 24-h ABP control; confirms dose equivalence in mild-moderate hypertension.
Does cilazapril 2.5 mg or 5 mg once daily reduce ambulatory blood pressure compared to placebo in patients with mild to moderate essential hypertension?
Cilazapril 2.5 mg and 5 mg once daily provide equivalent 24-hour ambulatory blood pressure reduction in patients with mild to moderate essential hypertension.
Lacourcière et al. (1991) studied this question.
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