Key result
Administration of red ginseng at /kg/day for 3 weeks reduced blood triglyceride levels and specific free fatty acids in healthy horses.
Why the study?
This study was conducted to investigate the potential benefits of red ginseng administration on lipid metabolism and individual free fatty acid profiles in healthy horses.
Does red ginseng reduce blood triglyceride levels and modulate free fatty acid profiles in healthy horses?
RCT (n=8)
Randomly divided
No
Does red ginseng reduce blood triglyceride levels and modulate free fatty acid profiles in healthy horses?
Red ginseng administration for 3 weeks significantly reduced blood triglyceride levels and specific free fatty acids in healthy horses without notable adverse effects.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for lipid modulation in equines; should not yet change clinical practice.
This study investigated the potential benefits of the administration of red ginseng (RG) on lipid metabolism and the profiles of individual free fatty acids (FFAs) in healthy horses. Eight healthy horses, raised under similar conditions, were randomly divided into two groups, each comprising four horses. The experimental group received powdered RG (600 mg/kg/day) mixed with a carrier, and the control group received only the carrier. The parameters associated with lipid metabolism and probable adverse effects were evaluated in both groups after 3 weeks. The computational molecular networking (MN) approach was applied to analyze the FFA profiles. The results indicated that RG administration significantly reduced blood triglyceride levels in the experimental group. Analysis of the FFAs using MN revealed significant decreases in specific types of FFAs (C12:0, dodecanoic acid; C14:0, myristric acid; C18:1, oleic acid; C18:2, linoleic acid). RG consumption did not produce significant adverse effects on the renal, hepatic, and immune functions. Thus, RG was found to effectively modulate lipid metabolism and the levels of individual FFAs. The application of the MN for the analysis of FFAs represents a novel approach and can be considered for future research.
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Kwak et al. (2024) conducted an RCT in Healthy horses (n=8). Red ginseng (Panax ginseng) vs. Carrier alone (molasses and water) was evaluated on Blood triglyceride levels (mg/dL) (p=<0.05). Administration of red ginseng at /kg/day for 3 weeks reduced blood triglyceride levels and specific free fatty acids in healthy horses.
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