Population
Rat model of hypertension induced by aortic banding just proximal to the renal artery
Comparison
Aortic banding vs Normal rats
Design
Preclinical
Authors
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Rat aortic banding model links hypertrophy to ATPase activity without MHC shift; leaves open human translation and clinical relevance.
Hypertension-induced aortic hypertrophy in rats is associated with increased myofibrillar ATPase activity but no change in myosin heavy chain isoform distribution.
Stephens et al. (1991) studied this question.
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