Key result
Essential hypertension was associated with higher Ea and Ees compared to healthy controls, and hypertensive females had lower Ea/Ees than control females.
Why the study?
How do blood pressure and sex impact heart-vessel coupling in patients with essential hypertension?
Case-Control (n=141)
How do blood pressure and sex impact heart-vessel coupling in patients with essential hypertension?
Essential hypertension is associated with altered heart-vessel coupling, particularly in females where coupling appears more easily damaged.
Answers are grounded in this paper and cite their sources.
May indicate greater vulnerability of ventricular-arterial coupling in hypertensive females; hypothesis-generating and requires prospective validation.
BACKGROUND/AIM: This study aimed to investigate the impact of blood pressure and sex on heart-vessel coupling in patients with essential hypertension via ultrasound. MATERIALS AND METHODS: We studied 76 patients with essential hypertension (48 males and 28 females) and 65 healthy controls (33 males and 32 females). Coupling parameters were obtained using ultrasound technology combined with brachial artery blood pressure measurement. RESULTS: The Ea and Ees were higher in the hypertension group than in the control group (P < 0.01), with no statistically significant difference in Ea/Ees between the two groups (P >0.05). After subjects were classified by sex, the Ea and Ees of males and females in the hypertension group were higher than those in the control group (P < 0.05 or P < 0.01), while the Ea/Ees was lower in hypertensive females than in control females (P < 0.05). CONCLUSION: In female patients with essential hypertension, heart-vessel coupling was easily damaged, and systolic blood pressure was associated with heart-vessel coupling damage to some extent.
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Hao et al. (2016) conducted a case-control in Essential hypertension (n=141). Essential hypertension vs. Healthy controls was evaluated on Heart-vessel coupling parameters (Ea, Ees, and Ea/Ees) (p=< 0.01). Essential hypertension was associated with higher Ea and Ees compared to healthy controls, and hypertensive females had lower Ea/Ees than control females.
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