Key result
Ischemic stroke with atrial fibrillation in U.S. adults aged ≥65 resulted in an age-adjusted mortality rate of 6.75 per 100,000 (95% CI 6.70-6.80) from 1999 to 2020, with rates rising after 2010.
Why the study?
Atrial fibrillation is a significant contributor to ischemic stroke risk and mortality in aging populations, prompting an evaluation of national mortality trends and disparities from 1999 to 2020.
Population
Individuals aged >= 65 years with death certificates listing ischemic stroke and AF in the US
Comparison
Demographic, urbanization, and geographic regional subgroups over time
Design
CDC WONDER database cross-sectional analysis
Authors
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May signal gaps in AF prevention for older adults; leaves open causal factors and intervention effects.
Cross-Sectional (n=62,443)
Yes
Mortality rates from ischemic stroke with atrial fibrillation in older US adults have increased significantly since 2010, highlighting the need for improved stroke prevention strategies and addressing regional and demographic disparities.
Assad et al. (2025) conducted a cross-sectional in Ischemic stroke with atrial fibrillation (n=62,443). Ischemic stroke with atrial fibrillation was evaluated on Age-adjusted mortality rate (AAMR) per 100,000 (95% CI 6.70-6.80). Ischemic stroke with atrial fibrillation in U.S. adults aged ≥65 resulted in an age-adjusted mortality rate of 6.75 per 100,000 (95% CI 6.70-6.80) from 1999 to 2020, with rates rising after 2010.
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