Why the study?
Is the ACE gene DD genotype associated with an increase in left ventricular mass index in patients with type 2 diabetes mellitus?
Population
289 non-insulin-dependent diabetes mellitus (NIDDM) subjects without known coronary artery disease
Comparison
ACE gene DD genotype vs ACE gene II and ID genotypes
Design
Cross-sectional
Authors
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May support ACE DD genotype link to higher LVMI in diabetic men; hypothesis-generating and requires prospective confirmation.
Is the ACE gene DD genotype associated with an increase in left ventricular mass index in patients with type 2 diabetes mellitus?
The ACE gene DD genotype is independently associated with increased left ventricular mass in men with type 2 diabetes mellitus.
R Estacio (1999) studied this question.
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