Why the study?
Does quinapril dose-dependently improve neurohumoral and haemodynamic parameters in patients with moderate heart failure?
Does quinapril dose-dependently improve neurohumoral and haemodynamic parameters in patients with moderate heart failure?
Chronic ACE inhibition with quinapril produces dose-dependent neurohumoral improvements in moderate heart failure, supporting the use of appropriately high doses.
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Supports higher quinapril dosing for maximal effect in moderate HF; extends RCT evidence on dose-dependent ACE inhibition.
Nussberger et al. (1994) studied this question.
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